Bromphen syrup is a prescription medication that contains two active ingredients – dextromethorphan hydrobromide and phenylpropanolamine. It is used to treat symptoms of the common cold, coughs, and upper respiratory allergies and infections. Some common reasons doctors may prescribe Bromphen syrup include:
Treating Coughs
One of the main uses of Bromphen syrup is to help suppress coughs. The dextromethorphan component acts as a cough suppressant, helping to reduce the urge to cough. This can provide relief when you have a wet or dry cough associated with colds, flu, bronchitis, or other upper respiratory infections. The effects last for 4-6 hours.
Some research shows dextromethorphan reduces the frequency of coughing fits and has antitussive (cough suppressing) effects comparable to codeine, a narcotic cough medicine. However, dextromethorphan doesn’t have the same potential for addiction or other side effects as opioid medications.
Relieving Nasal Congestion
Bromphen syrup also contains the oral nasal decongestant phenylpropanolamine. This ingredient helps to narrow swollen blood vessels in the nasal passages. This can relieve congestion and symptoms like a stuffy or runny nose that accompany colds, allergies, sinusitis, and other upper respiratory conditions.
Studies show phenylpropanolamine reduces resistance in the nasal cavity, allowing for better airflow and breathing within 30-60 minutes of taking the medication. The decongestant effects typically last for 4-6 hours.
Treating Allergy Symptoms
Doctors may prescribe Bromphen syrup to help relieve allergy symptoms like sneezing, watery eyes, runny nose, and sinus pressure. The phenylpropanolamine component works as a decongestant, while the dextromethorphan can reduce postnasal drip from allergic rhinitis that triggers coughs or sore throat.
One study found that an oral decongestant/antitussive combination drug was effective at alleviating rhinorrhea (runny nose), sneezing, nasal obstruction, and cough in patients with seasonal allergic rhinitis.
How Long Does Bromphen Syrup Last?
Bromphen syrup typically provides relief from symptoms for 4 to 6 hours after taking a dose. The duration of action may vary slightly depending on the individual and dosage taken.
The dextromethorphan component starts working within 15-30 minutes to suppress coughs. Its effects tend to peak within 1-2 hours and last for around 4-6 hours.
The phenylpropanolamine decongestant also begins working within 30 minutes. Its effects reach maximum strength within 1-2 hours and persist for about 4-6 hours after taking a dose.
Bromphen Syrup Dosage
The dosage amount of Bromphen syrup depends on the age of the patient:
- Age 4-5: 5 mL every 4 hours as needed
- Age 6-11: 10 mL every 4 hours as needed
- Age 12 and older: 20 mL every 4 hours as needed
Do not exceed 6 doses or 120 mL in 24 hours. It’s important to carefully follow dosage directions and not take more than prescribed without consulting your doctor.
How to Take Bromphen Syrup
Bromphen syrup is taken by mouth. It is usually mixed with water but can be mixed with juice or other beverages if preferred. The medication has a strong bitter taste, so taking it with something that masks the flavor can make it easier to swallow.
Some tips for taking Bromphen syrup include:
- Measure out the prescribed dose using an oral syringe or other dosing device. Do not use regular silverware to measure out doses.
- Take the medication with a full glass of water or juice – this helps get the entire dose swallowed.
- Drink the entire mixture right away – do not let it sit after mixing.
- Rinse your mouth with water or brush your teeth after taking Bromphen to help minimize the bitter aftertaste.
- Avoid taking the medication on an empty stomach as it may cause nausea or stomach upset.
- Take doses at least 4 hours apart to maintain consistent symptom relief.
What to Expect When Taking Bromphen Syrup
Here are some things to expect when taking Bromphen syrup as prescribed:
- Relief from coughing and congestion within 30-60 minutes
- Suppressed cough allowing for more restful sleep
- Improved airflow and ability to breathe through your nose
- Decreased sneezing, runny nose, and postnasal drip
- Symptom relief lasting 4-6 hours per dose
- Bitter, unpleasant taste
- Possible side effects like drowsiness, headache, nausea, or restlessness (see next section for details)
- Avoid driving or operating heavy machinery until you know how the medication affects you
The benefits of Bromphen syrup should outweigh any minor side effects. However, contact your doctor if symptoms do not start improving within a few doses or if side effects become severe.
Bromphen Syrup Side Effects
Some potential side effects of Bromphen syrup include:
- Drowsiness – Dextromethorphan can cause drowsiness or sedation in some people. Avoid driving or hazardous activities after taking until you know how you respond.
- Dizziness – Bromphen can sometimes make people feel lightheaded or dizzy.
- Nausea, vomiting, stomach upset – This medication may irritate the stomach, especially if taken on an empty stomach.
- Headache – Headaches are a possible side effect of Bromphen syrup.
- Restlessness – Some people may feel jittery or agitated after taking dextromethorphan.
- Rapid heartbeat – Phenylpropanolamine may cause a rapid heart rate in some individuals.
These side effects are usually mild at recommended therapeutic doses. Taking too much Bromphen syrup can increase the risk of adverse effects. Seek medical advice if any symptoms seem severe or don’t go away.
Serious Side Effects
In rare cases, Bromphen syrup may cause serious side effects requiring emergency care. These include:
- Hives, rash, itching, swelling
- Wheezing, chest tightness, trouble breathing
- Severe dizziness or fainting
- Uncontrolled shaking or twitching
- Irregular heartbeat
- Hallucinations
- Seizures
Stop taking Bromphen syrup and seek immediate medical help if any signs of a serious allergic reaction or adverse effects develop.
Bromphen Syrup Drug Interactions
Bromphen syrup may interact with certain medications. Some possible drug interactions include:
- MAO inhibitors – Avoid taking Bromphen if you take MAO inhibitor antidepressants like phenelzine and tranylcypromine, or have stopped an MAOI within the past 14 days. This combination could cause a dangerous rise in blood pressure.
- SSRIs – Using Bromphen with selective serotonin reuptake inhibitors like fluoxetine (Prozac) increases the risk of serotonin syndrome, causing confusion, agitation, headache, rapid heartbeat, shivering, sweating, and other symptoms.
- Tricyclic antidepressants – Bromphen may enhance the effects of TCAs like amitriptyline, leading to greater side effects.
- Cough suppressants – Avoid using other cough medicines when taking Bromphen syrup to prevent an overdose.
- Nasal decongestant sprays or pills – Don’t use other decongestants with Bromphen unless advised by your doctor, as excessive doses can cause side effects.
Always inform your doctor about all medications you take, including any herbal supplements, to check for possible interactions with Bromphen.
Warnings and Precautions When Taking Bromphen Syrup
Here are some important warnings to consider before taking Bromphen syrup:
- Don’t exceed the recommended dosage. An overdose can be fatal.
- Measure doses carefully using an appropriate measuring device like an oral syringe.
- Don’t take for longer than advised by your doctor.
- Don’t take with any other cough/cold or decongestant medications unless instructed to do so.
- Use caution when driving or operating machinery until you know how this medication affects you.
- Don’t take if you’ve had an MAO inhibitor in the past 14 days.
- Don’t use if you have glaucoma, heart disease, hypertension, thyroid problems, diabetes, enlarged prostate, or difficulty urinating.
- Tell your doctor if you have kidney disease, liver disease, COPD, or asthma before using.
- Don’t take if you have a chronic cough related to smoking, asthma, or emphysema.
Bromphen is not recommended for use in children under 4 years old. Pregnant women should only take Bromphen syrup if the benefits clearly outweigh potential risks and under medical supervision.
What to Do if You Miss a Dose
If you miss a dose of Bromphen syrup, take it as soon as you remember. However, if it’s close to the time for your next scheduled dose, skip the missed dose. Avoid taking two doses together to make up for a missed one.
Don’t exceed four doses in any 24-hour period. For the best results, maintain a consistent schedule and try to take Bromphen syrup around the same times each day.
How to Store Bromphen Syrup
Bromphen syrup should be stored at room temperature away from excess heat, moisture, and direct light. Keep the medication bottle tightly closed when not in use.
Don’t freeze Bromphen syrup. It can typically be stored at room temperature below 77°F (25°C) for up to two years from the date of manufacture. Discard any unused syrup after the expiration date on the package has passed.
The syrup should be discarded 14 days after opening even if the expiration date hasn’t passed yet. Always keep Bromphen syrup in a secured location out of the reach of children and pets.
Is Bromphen Syrup Addictive?
Bromphen syrup is not considered addictive when taken at doctor-recommended dosages for short treatment courses of cough or congestion. There is a potential for dependence and abuse with the dextromethorphan component, however.
Dextromethorphan acts on opioid receptors in the brain similarly to narcotic pain relievers. Some people have misused dextromethorphan at very high doses to try to get high. This can be extremely dangerous with side effects like:
- Distorted perceptions of time and space
- Dizziness and loss of coordination
- Nausea and vomiting
- Increased heart rate and blood pressure
- Overdose reactions like seizures, coma, and death
Never take more Bromphen syrup than prescribed or use it longer than advised. Speak to your doctor if you have a history of substance abuse before using this medication.
Common Questions About Bromphen Syrup
Is Bromphen syrup an antibiotic?
No, Bromphen syrup is not an antibiotic. It contains dextromethorphan as a cough suppressant and phenylpropanolamine as a decongestant. Antibiotics fight against bacterial infections, but Bromphen works against symptoms of colds and respiratory allergies which are usually caused by viruses.
Does Bromphen syrup make you sleepy?
One of the most common side effects of Bromphen syrup is drowsiness. The dextromethorphan component has sedating effects that can make some people feel tired or sleepy after taking a dose. Using alcohol or other medicines that cause drowsiness along with Bromphen can worsen this effect.
Can I drive after taking Bromphen syrup?
It’s best to avoid driving or operating heavy machinery when first starting Bromphen until you know how it affects you. Dizziness, drowsiness, and blurred vision are possible side effects that could impair your ability to drive safely. Wait to see how each dose impacts you before driving.
Can children take Bromphen syrup?
Bromphen syrup can be given to children as young as 4 years old. However, the dosage must be reduced for younger patients based on their age and weight. Always follow dosing guidelines carefully for children and only give Bromphen under medical supervision in pediatric patients.
What does Bromphen syrup taste like?
Bromphen syrup has a very bitter, unpleasant taste according to many patients. It’s best to mix each dose with a full glass of juice, water, soda, or something similar to help mask the flavor. After taking it, rinse your mouth out to help reduce the bitter aftertaste.
Can Bromphen syrup be mixed with alcohol?
It’s not recommended to consume alcohol when taking Bromphen syrup. Alcohol intensifies the sedative effects of the dextromethorphan, increasing side effects like dizziness, drowsiness, and slowing your breathing rate. Combining the two further impairs physical abilities and motor skills.
Is Bromphen syrup an antihistamine?
No, Bromphen syrup does not contain an antihistamine. Antihistamines like diphenhydramine (Benadryl) help relieve allergy symptoms like runny nose, watery eyes, and sneezing. Bromphen instead contains a decongestant called phenylpropanolamine to reduce nasal congestion associated with allergies.
Conclusion
Bromphen syrup is an effective medication used for relieving coughs, congestion, and upper respiratory allergy and infection symptoms. When taken as directed, it can provide 4-6 hours of relief per dose from coughs, stuffy nose, postnasal drip, and sneezing. Side effects are usually mild but may include drowsiness, dizziness, headache, nausea, or restlessness.
Use caution when driving or operating machinery until you know how Bromphen affects you. Avoid alcohol and be aware of potential interactions with other medications you take. Never exceed the prescribed dosage and follow usage instructions carefully, especially when giving Bromphen syrup to children. Speak with your doctor if you have any other questions about the proper use of this medication.